Last update
3/12/2026
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 4 Reviews
8.3
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
33.3 mg
37%
Vitamin D (as D3 Cholecalciferol)
8.3 mcg (333 IU)
42%
Calcium (Elemental)(from Microcrystalline Hydroxyapatite)
333.3 mg
26%
Magnesium (as Magnesium Oxide)
116.7 mg
28%
Zinc (as Zinc L-Methionine Sulfate)
3.3 mg
30%
Copper (as Copper Gluconate)
0.333 mg
37%
Manganese (as Manganese Citrate)
0.333 mg
14%
Vitamin K2 (as Natural MK-7 [Menaquinone-7])
15 mcg
†
Boron (as Boron Citrate)
1 mg
†
Top Medical Research Studies
9
We examined the effectiveness of the Missouri Osteochondral Preservation System (MOPS) compared to standard preservation methods for treating knee pain after osteochondral allograft (OCA) transplantation.
Our study revealed that patients receiving MOPS shell grafts experienced significant improvements in pain and function after two years.
Specifically, MOPS showed an impressive 98% functional graft survival rate, contrasted with 83% for standard methods.
Moreover, unipolar patella allograft patients reported the greatest relief and functionality, indicating that MOPS may offer superior short-term outcomes for knee pain.
Our study revealed that patients receiving MOPS shell grafts experienced significant improvements in pain and function after two years.
Specifically, MOPS showed an impressive 98% functional graft survival rate, contrasted with 83% for standard methods.
Moreover, unipolar patella allograft patients reported the greatest relief and functionality, indicating that MOPS may offer superior short-term outcomes for knee pain.
Read More
Most Useful Reviews
9
Significant pain relief
2 people found this helpful
This supplement seems to be my solution. I've tried various supplements targeting the musculoskeletal system. Due to this year's persistent rain and a personal tragedy, all my joints and lower back (intervertebral hernias) have been painful. I discovered that a deficiency in calcium can also lead to joint discomfort, which led me to choose this supplement. While I wouldn't claim a miracle, my pains have considerably reduced, and this improvement is undoubtedly linked to this supplement, as I am not currently using painkillers or any other medications. It's unfortunate that regular use isn't advisable. I also appreciate the composition, though I prefer taking magnesium at night as it's more beneficial for me then. Overall, I am very satisfied with this supplement and have no desire to experiment with others.
Read More
7.5
Less joint crunching
7 people found this helpful
I ordered this complex due to its adequate doses of vitamin D, C, and K2, which enhance calcium absorption. After taking it with type II collagen, I found that the crunching in my knee and elbow joints has significantly decreased.
Read More
7.5
Knees hurt less
2 people found this helpful
I can confirm it’s working; my knees crack less. As I pray often, the pain was bothersome, but now it’s much reduced, allowing me to perform my movements with greater ease.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
- All Researches
9
We examined the effectiveness of the Missouri Osteochondral Preservation System (MOPS) compared to standard preservation methods for treating knee pain after osteochondral allograft (OCA) transplantation.
Our study revealed that patients receiving MOPS shell grafts experienced significant improvements in pain and function after two years.
Specifically, MOPS showed an impressive 98% functional graft survival rate, contrasted with 83% for standard methods.
Moreover, unipolar patella allograft patients reported the greatest relief and functionality, indicating that MOPS may offer superior short-term outcomes for knee pain.
Our study revealed that patients receiving MOPS shell grafts experienced significant improvements in pain and function after two years.
Specifically, MOPS showed an impressive 98% functional graft survival rate, contrasted with 83% for standard methods.
Moreover, unipolar patella allograft patients reported the greatest relief and functionality, indicating that MOPS may offer superior short-term outcomes for knee pain.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Significant pain relief
2 people found this helpful
This supplement seems to be my solution. I've tried various supplements targeting the musculoskeletal system. Due to this year's persistent rain and a personal tragedy, all my joints and lower back (intervertebral hernias) have been painful. I discovered that a deficiency in calcium can also lead to joint discomfort, which led me to choose this supplement. While I wouldn't claim a miracle, my pains have considerably reduced, and this improvement is undoubtedly linked to this supplement, as I am not currently using painkillers or any other medications. It's unfortunate that regular use isn't advisable. I also appreciate the composition, though I prefer taking magnesium at night as it's more beneficial for me then. Overall, I am very satisfied with this supplement and have no desire to experiment with others.
Read More
7.5
Less joint crunching
7 people found this helpful
I ordered this complex due to its adequate doses of vitamin D, C, and K2, which enhance calcium absorption. After taking it with type II collagen, I found that the crunching in my knee and elbow joints has significantly decreased.
Read More
7.5
Knees hurt less
2 people found this helpful
I can confirm it’s working; my knees crack less. As I pray often, the pain was bothersome, but now it’s much reduced, allowing me to perform my movements with greater ease.
Read More
7.5
Excellent for pregnancy
I purchased this for my sister during pregnancy as her knee pain from excess weight was troubling her. She praised the product significantly.
Read More
Frequently Asked Questions
7.5
Less joint crunching
7 people found this helpful
I ordered this complex due to its adequate doses of vitamin D, C, and K2, which enhance calcium absorption. After taking it with type II collagen, I found that the crunching in my knee and elbow joints has significantly decreased.
9
We examined the effectiveness of the Missouri Osteochondral Preservation System (MOPS) compared to standard preservation methods for treating knee pain after osteochondral allograft (OCA) transplantation.
Our study revealed that patients receiving MOPS shell grafts experienced significant improvements in pain and function after two years.
Specifically, MOPS showed an impressive 98% functional graft survival rate, contrasted with 83% for standard methods.
Moreover, unipolar patella allograft patients reported the greatest relief and functionality, indicating that MOPS may offer superior short-term outcomes for knee pain.
Our study revealed that patients receiving MOPS shell grafts experienced significant improvements in pain and function after two years.
Specifically, MOPS showed an impressive 98% functional graft survival rate, contrasted with 83% for standard methods.
Moreover, unipolar patella allograft patients reported the greatest relief and functionality, indicating that MOPS may offer superior short-term outcomes for knee pain.
References
- Buyuk AF, Stannard JP, Rucinski K, Crecelius CR, Cook JL. The Missouri Osteochondral Preservation System Is Associated With Better Short-Term Outcomes Than Standard Preservation Methods When Performing Osteochondral Allograft Transplantation Using Shell Grafts for Patellofemoral Lesions. Arthroscopy. 2023;39:650. 10.1016/j.arthro.2022.10.007
Data last updated:
